11th ICQ10A CONGRESS
UNVEILING THE ESSENTIAL ROLE OF COQ IN HEALTH
VENUE:
Niels K. Jerne Auditorium
University of Copenhagen
16th-19th June, 2025
LODGEMENT
Scandic Sluseholmen
Located at Molestien 11, Copenhagen. It is approximately 5 miles from the event site. The EC members and invited speakers will be booked here.
Location
promotional code (Before 26th May 2025): ECCS
Scandic Copenhagen
Located at Vester Søgade 6, Copenhagen. It is approximately 1.5 miles from the event site.
Location
promotional code (Before 26th May 2025): ECCS
Scandic Falkoner
Located at Falkoner Alle 9, Copenhagen. It is approximately 2.5 miles from the event site.
Location
promotional code (Before 26th May 2025): ECCS
Cab Inn Scandinavia
Located at Vodroffsvej 55, Copenhagen. It is approximately 2 miles from the event site. This Hotel is slightly cheaper. ICQ10A has already pre-booked 20 rooms here. Using the promotional code you will be redirected directly to the site.
Location
promotional code (Before 16th May 2025): BLKQ10SYM
Early registration
(before 1st April, 2025)
REGULAR REGISTRATION: 350 €
ICQA MEMBERS: 200 €
STUDENTS*: 150 €
SOCIAL DINNER: 60€
INSCRIPTIONS
Late registration
(after 1st April, 2025)
REGULAR REGISTRATION: 400 €
ICQA MEMBERS: 250 €
STUDENTS*: 200 €
SOCIAL DINNER: 60€
PROGRAM
EDUCATION DAY: MONDAY 16th June
10:30-17:45 h
PRE-CONGRESS LIGHTNING TALKS
COENZYME Q AT THE CROSSROADS OF METABOLIC PATHWAYS IN MITOCHONDRIAL-RELATED DISEASES
A FREE activity for college undergraduates and recent graduates in biomedical disciplines or medicine and for congress delegates.
Availability after FREE subscription.
PROGRAM:
MASTER CLASS
10:30-12:00 h
Q REDOX AND CELL METABOLISM
CHAIR: MARIA LUISA GENOVA
DAVID G. NICHOLLS
Buck Institute for Age Research, Mitochondrial Physiology, Novato, California, USA.
LUNCH
12:00-13:30 h
MASTER CLASS
13:30-14:30 h
Q REDOX AND CELL METABOLISM
DAVID G. NICHOLLS
Buck Institute for Age Research, Mitochondrial Physiology, Novato, California, USA.
COFFEE BREAK
14:30-15:00 h
ROOM A
HANDS-ON SESSION 1
15:00-16:00 h
SPECTROSCOPY AND MODELLING OF Q-BINDING ENZYME DETAILS
ARTUR OSYCZKA
Department of Molecular Biophysics, Jagiellonian University, Poland.
ROOM B
DEMO SESSION 1
15:00-16:00 h
OROBOROS, Q REDOX POOL MEASUREMENTS
LUIZA CARDOSO & MATEUS GRINGS
Oroboros Instruments Mitochondria and Cell Research, Universität Innsbruck, Austria.
COFFEE BREAK AND CLASS SWITCH
16:00-16:45 h
ROOM A
HANDS-ON SESSION 2
16:45-17:45 h
SPECTROSCOPY AND MODELLING OF Q-BINDING ENZYME DETAILS
ARTUR OSYCZKA
Department of Molecular Biophysics, Jagiellonian University, Poland.
ROOM B
DEMO SESSION 2
16:45-17:45 h
OROBOROS, Q REDOX POOL MEASUREMENTS
LUIZA CARDOSO & MATEUS GRINGS
Oroboros Instruments Mitochondria and Cell Research, Universität Innsbruck, Austria.
FIRST DAY: TUESDAY 17th June
8.30 h
OPENING OF RECEPTION OF PARTICIPANTS
10:00 -11:00 h
OPENING CEREMONY
10:00 – 11:00 h
OPENING CONFERENCE
CHAIR: PLÁCIDO NAVAS
SIEGFRIED HEKIMI
Department of Biology, McGill University, Montreal, Quebec, Canada.
TITLE: “Coenzyme Q from worms to mice and from drugs to new cell biology”
FIRST SESSION
11:00-13:00 h
NEW ADVANCES IN COQ BIOSYNTHESIS
CHAIRS: ANDREA MATTEVI AND LAURA FORMENTINI
ANDREA MATTEVI
Department of Biology and Biotechnology “Lazzaro Spallanzani”, University of Pavia, Pavia, Italy.
TITLE: “In vitro reconstruction unveils the molecular mechanisms of the COQ”
LAURA FORMENTINI
Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa (CBMSO, UAM-CSIC), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
TITLE: “Substrate-dependent Mitochondrial Efficiency: A New Metabolon Involved in the CoQ-Cycle.”
MAKOTO KAWAMUKAI
Department of Life Sciences, Faculty of Life and Environmental Sciences, Shimane University, Japan.
TITLE: “Novel factors that regulate CoQ10 synthesis in fission yeast”
- Nicola Rizzardi
Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
TITLE: “A combination of Coenzyme Q10, pyruvate, and vitamin B3 restores bioenergetic function under metabolic stress and protects astrocytoma cells from apoptosis and inflammation.”
Department of Pharmacy and Biotechnology, Alma Mater studio rum, university of Bologna, via Irnerio 48, Bologna, Italy.
TITLE: “Coenzyme Q10 supplementation reverses bioenergetic defects caused by mutant SPART in patient-derived fibroblast.”
LUNCH
13:00-15:00 h
MASTER CLASS
14:30-15:00 h
HOW TO WRITE A PAPER FOR PUBLICATION
Dr. FRANKLIN ROSENFELD
Baker Heart and Diabetes Institute, Melbourne, Vic, Australia; Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Vic, Australia.
SECOND SESSION
15:00-16:30 h
USE OF PRECURSORS TO INCREASE COENZYME Q BIOSYNTHESIS
CHAIRS: DAVID J. PAGLIARINI AND LUIS CARLOS LÓPEZ
DAVID J. PAGLIARINI
Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.
TITLE: “CoQ deliverables: providing precursors to mitochondria”
LUIS CARLOS LÓPEZ
Department of Physiology, Biomedical Research Center, University of Granada, Spain
TITLE: “Exploring the Therapeutic Modulation of Endogenous CoQ Biosynthesis”
- Dr. R. Osypchuk
Nizhyn Mykola Gogol State University, Ukraine
TITLE: “Seed priming with compositions of precursors and mediators of coenzyme Q biosiynthesis improved its content and redox status in basil seeds.”
- Dr. Alba Pesini
Department of Neurology, Columbia University Medical Center, New York, NY, 10032, USA
TITLE: “Disruption of lipid metabolism in neuronal models of Coenzyme Q10 deficiency.”
COFFEE BREAK
16:30-17:00 h
WALKING POSTER SESSION
17:00-18:30 h
Dynamic presentation of posters by attendants to the evaluation committee and participants.
5 min presentation per poster (3 min + 2 min questions).
WELCOME RECEPTION
18:30-20:00 h
SECOND DAY: WEDNESDAY 18th June
THIRD SESSION
8.30-10:30 h
PRIMARY AND SECONDARY DEFICIENCIES
CHAIRS: LEONARDO SALVIATI AND GLORIA BREA CALVO
LEONARDO SALVIATI
Clinical Genetics Unit, Department of Women and Children’s Health, University of Padova, 35128 Padova, Italy.
TITLE: “Genetic defects and clinical phenotypes associated with primary coenzyme Q deficiency”
GLORIA BREA-CALVO
Department of Physiology, Anatomy and Cell Biology, Pablo de Olavide University, Seville, Spain.
TITLE: “Exploring phenotypic heterogeneity in Coenzyme Q biosynthesis defects using zebrafish”
AP-HP, Epilepsy Unit, Department of Neurology, Reference Center of Rare Epilepsies, ERN-EpiCare, Pitié-Salpêtrière Hospital, Paris, France
TITLE: “Two patients with COQ8A deficiency improved under new ubiquinone nano formulation.”
BPGbio Inc., Framingham, MA, 01701
TITLE: “BPM31510 Treatment Demonstrates Therapeutic CoQ10 Restoration in Experimental CoQ Deficiency Models As Assessed by a Spatial and LC MS/MS based Quinomics.”
TITLE: “BPM31510 Treatment Reverses the Warburg Effect in a Quinone Deficient C6 Glioma Resulting in Metabolic Rewiring and Efficacy.”
Department of Chemistry & Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, CA 90059, USA.
TITLE: “CoQ on the Move: Autophagic Machinery and Vps1 Function in the Uptake of Exogenous CoQ.”
COFFEE BREAK
10:30-11:00 h
FOURTH SESSION
11:00-13:15 h
DIFFERENT CLINICAL ASPECTS OF CoQ
CHAIRS: YASUYOSHI WATANABE AND MARCO SPINAZZI
YASUYOSHI WATANABE
Kobe University Graduate School of Science, Technology and Innovation and RIKEN Center for Biosystems Dynamics Research, Kobe, Osaka, Japan.
TITLE: “PET imaging of 11C- labeled Ubiquinol-10, the reduced form of Coenzyme Q10, for pharmacokinetics in human”
MARCO SPINAZZI
Neuromuscular Reference Center, Department of Neurology, CHU Angers, Angers, France.
TITLE: “Role of ferroptosis in mitochondrial diseases”
MASSIMO SANTORO
Department of Biology, University of Padua, Padua, Italy.
TITLE: “CoQ10 and UBIAD1 regulate cell stiffening and membrane signaling in breast cancer”
- Dr. Niven R. Narain
BPGbio, USA
TITLE: “Initial experience using intravenous BPM31510IV to restore CoQ10 in pediatric patients with CoQ10 deficiency.”
- Dr. Renata L. S. Goncalves
Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health; Boston, MA, USA.
TITLE: “CoQ Deficiency Drives Reverse Electron Transport and Disrupts Hepatic Metabolic Homeostasis in Obesity.”
- Dr. Jukka Kallijärvi
Folkhälsan Research Center; Helsinki, Finland
TITLE: “GRACILE syndrome patient mutation knock-in mouse model: A valuable resource for studies of complex III and CoQ pathophysiology.”
LUNCH
13.15-14:30 h
Including, experts corner from 14:00 to 14:30
SINGLE SESSION
14:00-14:30 h
Publishing manager, Journal Relations Specialist at MDPI.
MDPI- Antioxidants
TITLE: “Introducing Antioxidants (IF 6.0), the Joint Special Issue, and MDPI Publication Services.”
FIFTH SESSION
14:30-16:30 h
CoQ IN COGNITIVE DEFICIENCY AND PERSISTENT COVID
CHAIRS: FRANKLIN ROSENFELDT AND ANNA GVOZDJAKOVA
FRANKLIN ROSENFELDT
Baker Heart and Diabetes Institute, Melbourne, Vic, Australia; Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Vic, Australia.
TITLE: “Coenzyme Q10 and Chronic Fatigue syndrome: implications for Long Covid.”
ANNA GVOZDJAKOVA
Pharmacobiochemical Laboratory of 3rd Medical Department, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.
TITLE: “Coenzyme Q10 and Long Covid.”
MADELEINE NANKIVELL
Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
TITLE: “Coenzyme Q10 and Cognition: A review.”
Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy
TITLE: “Role of Coenzyme Q10 in mitochondrial dysfunction and oxidative damage in RETT syndrome.”
COFFEE BREAK
16:15-17:00 h
ROUND TABLE
17:00-18:30 h
HOW TO START CoQ10 SUPPLEMENTATION IN A PATIENT?
CHAIRMAN
PLÁCIDO NAVAS
PARTICIPANTS
FRANZ ENZMANN, ALICE ZEMLJIC-HARPF, LEONARDO SALVIATI, RAFAEL ARTUCH, FRANKLIN ROSENFEDT.
END OF SECOND DAY
18:30 h
WELCOME DRINKS
19:00 h
SOCIAL DINNER
19:30 h
THIRD DAY: THURSDAY 19th June
SIXTH SESSION
8.30-10:30 h
THE KEY ROLE CoQ IN MITOCHONDRIAL PHYSIOLOGY
CHAIRS: CATHERINE F. CLARKE AND JOSÉ ANTONIO ENRIQUEZ
CATHERINE F. CLARKE
Department of Chemistry & Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, California, USA.
TITLE: “Chaperones, Contact Sites, and Membrane Lipid Transport – a Nexus for Biosynthesis and Trafficking of CoQ”
JOSÉ ANTONIO ENRÍQUEZ
Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
TITLE: “Metabolic channeling in the electron transport chain.”
SHARON CELESTE MORLEY
Department of Pediatrics, Infectious Diseases Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA
TITLE: “Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease through altered metabolic remodeling“
- Dr. Franz Enzmann
IMMA International Mitochondrial Medicine Association, Germany
TITLE: “MITOPHYSE® Mitochondria Control the Hypothalamic-Pituitary-Axes.”
COFFEE BREAK
10:30-11:00 h
SEVENTH SESSION
11:00-12:30 h
CoQ IN CARDIOVASCULAR DISEASE AND HEART FAILURE
CHAIRS: ALICE ZEMLJIC-HARPF AND ADAM C. STRAUB
ALICE ZEMLJIC-HARPF
Dep. of Anesthesiology, University of California, San Diego, La Jolla, and Veterans Affairs San Diego Healthcare System, San Diego, USA.
TITLE: “CoenzymeQ10 Statins, and the Heart Failure Pandemic: From Mouse to Mankind and Back”
ADAM C. STRAUB
Center for Microvascular Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA).
TITLE: “Cytochrome b5 Reductases and CoQ in Cardiovascular Health and Disease”
DANG VAN PHUOC
Faculty of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam.
TITLE: “Introduction of CoQ10 in Cardiology in Vietnam”
- Filomain Nguemo
Center for Physiology and Pathophysiology, Faculty of Medicine and University Hospital Cologne, University of Cologne
TITLE: “A nanoformulation of Ubiquinol and Selenium Promotes Proliferation of Human Induced Pluripotent Stem Cells.”
LUNCH
12.30-14:00 h
EIGHTH SESSION
14:00-15:15 h
BIOAVAILABILITY OF COENZYME Q10 AND SUPPLEMENTATION IN SPECIAL SITUATIONS
CHAIRS: IAIN HARGREAVES AND LUCA TIANO
IAIN HARGREAVES
School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
TITLE: “The utility of coenzyme Q10 in the treatment of neuronal mitochondrial dysfunction”
FABIO MARCHEGGIANI
Department of Life and Environmental Sciences (DISVA), Marche Polytechnic University, Ancona, Italy.
TITLE: “Evaluating Coenzyme Q10 in Skin Rejuvenation: Insights from Mitochondrial Function and Dynamics in Fibroblast Models.”
- Michele Guescini
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Italy
TITLE: “Coenzyme Q10 muscle delivery using exosome-mimetic nanovesicles.”
COFFEE BREAK
15:15- 15:45 h
NINTH SESSION
15:45-18:00 h
CoQ IN HEALTHY AGING
CHAIRS: STEEN LARSEN AND KEIICHI HIGUCHI
FRANK ROSENFELDT
Baker Heart and Diabetes Institute, Melbourne, Vic, Australia; Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Vic, Australia.
TITLE: “Q-symbio Study.”
ANGUS NIGHTINGALE
Bristol Heart Institute, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
TITLE: “The effectiveness and cost effectiveness of CoQ10 in heart failure – The CORAL Study.”
STEEN LARSEN
Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
TITLE: “Coenzyme Q10 supplementation and the aging muscle.”
KEIICHI HIGUCHI
Meio University, Graduate School of Sports and Health Science, Nago, Okinawa, Japan.
TITLE: “Health-promoting and cytoprotective effects of Ubiquinol administration.”
MADELEINE NANKIVELL
Faculty of Health, Arts and Design, Department of Psychological Science, Swinburne University of Technology, Victoria, Australia.
TITLE: “Investigating the effect of chronic supplementation with Ubiquinol on cognitive function and mood”
CLOSING CEREMONY / AWARDS CEREMONY
18:00-18:30 h
Award to the best poster and to the best young oral communication of 500 € each
Transfer payment
BANK: CAIXABANK
IBAN: ES90 2100 8410 2102 0002 3466
SWIFT / BIC: CAIXESBBXXX
PAYPAL: VISIT LINK BELLOW
EARLY INSCRIPTIONS:
Registration include payment of the registration and submission of the abstract to the Organizing Committee. Book of abstracts, coffee breaks and lunches.
Early registration must be completed before the 1st of March, 2025.
On line registration includes access to the sessions by on-line platforms and book of abstracts.
* Students, including doctorate students, may confirm their situation by certificate of study.
ORAL COMMUNICATIONS:
Students must indicate in the registration procedure that they can participate with an oral communication indicating the specific session.
The Academic Committee of each session will study the different communications and decide if they are going to be presented orally in each session or shown as poster.
SPONSORSHIP
Sponsors are welcome. We offer two levels of sponsorship:
1.- A fee of 400€ that includes acknowledgement in opening and closing ceremonies and logo in the program, website of the congress and in mailing and book of abstracts.
2.- A fee of 2500€ that includes acknowledgment in opening nd closing ceremonies and logo in the program, website of the congress, a table, with two chairs and points for electricity and the registration of one person including the access to sessions, book of abstracts, food and drinks of the conference
SPECIAL OFFERT
All the participants in the 11th ICQ10A Congress will have the opportunity to publish their work in an Special Issue of Antioxidants:
Unveiling the Essential Role of Coenzyme Q in Health
with a discount of 30% over the APC.
